Sirolimus chemoprevention supported in organ transplant recipients
In solid-organ transplant recipients diagnosed with cancer post-transplant, treatment with sirolimus reduces the risk of developing a subsequent skin cancer, US investigators report in JAMA Dermatology.
View ArticleNovartis announces FDA approval of Afinitor for progressive, nonfunctional...
Novartis today announced that the United States Food and Drug Administration approved Afinitor (everolimus) tablets for the treatment of adult patients with progressive, well-differentiated,...
View ArticleRare disease day focuses on new approach to finding treatment
2,200 babies will be born in the UK on 29th February, of which 30 will die of a rare disease before they are five years old.
View ArticlePCI with polymer-free BA9 drug-coated stent better than bare metal stent in...
Patients with acute coronary syndromes (ACS) who are at high risk for bleeding have significantly lower rates of target lesion revascularisation and fewer adverse events after undergoing percutaneous...
View ArticleATS releases new clinical practice guidelines for diagnosis, management of LAM
The American Thoracic Society and the Japanese Respiratory Society have published new clinical practice guidelines for the diagnosis and management of lymphangioleiomyomatosis (LAM), a rare lung...
View ArticleTCT 2016 features first report investigations on novel bioresorbable stents
The 28th annual Transcatheter Cardiovascular Therapeutics (TCT), the annual scientific symposium of the Cardiovascular Research Foundation featured a number of first report investigations on novel...
View ArticleStudy of new polymer-free DFS indicates non-inferior in-stent late lumen loss...
A first-in-human study of a new polymer-free drug-filled stent, which provides controlled drug elution from an internal lumen, indicated non-inferior in-stent late lumen loss at nine-months compared...
View ArticleOrbusNeich launches new Dual Therapy Stent for active vessel healing
OrbusNeich has announced the launch of its latest generation Dual Therapy Stent (DTS), the COMBO Plus.
View ArticleUC scientists take different approach to investigating how influenza spreads...
Influenza is a recurring global health threat that, according to the World Health Organization, is responsible for as many as 500,000 deaths every year, most due to influenza pneumonia, or viral...
View ArticleNew clinical trial examines potential role of drug combination therapy to...
Researchers at the University of Cincinnati begin a new clinical trial this fall, examining the potential role of a drug combination therapy to eliminate lymphangioleiomyomatosis (LAM) cells.
View ArticleATS and JRS publish new guidelines for diagnosis and management of LAM
The American Thoracic Society and the Japanese Respiratory Society have published additional clinical practice guidelines regarding four specific questions related to the diagnosis of...
View ArticleScientists develop new drug for treating skin lesions in rare intractable...
Scientists at Osaka University developed a new drug treating skin lesions in tuberous sclerosis complex (TSC), a rare intractable disease, a world first.
View ArticleClinical study shows efficacy, safety of novel drug-eluting stent with...
This first randomized clinical study of a polymer-coated zotarolimus-eluting stent (Resolute Onyx) that utilizes a novel thin-strutted metallic platform allowing for better x-ray visibility was shown...
View ArticleToxic effects of drugs in the lungs 'more widespread than thought'
A systematic review of research has revealed that the toxic effects on the lung of drugs commonly taken to treat a range of common conditions is much more widespread than thought.
View ArticleResearchers identify genetic component involved in development of familial...
Working with their colleagues from the University of Lyon, researchers from MedUni Vienna's Center for Pathobiochemistry and Genetics have discovered mutations in genes that regulate the metabolic...
View ArticleGene mutation discovery leads to novel treatment for patient with severe...
Faced with a preteen boy in pain and struggling to breathe from a severe, deteriorating rare condition, researchers at Children's Hospital of Philadelphia identified the responsible gene mutation and...
View ArticleDrug combination could improve survival of lung transplant patients
Lung transplantation can prolong the lives of patients with end-stage lung disease, but the median survival rate after lung transplant is less than six years, which has improved only slightly in recent...
View ArticleScientist proposes geroprotective strategies to reduce lethality of COVID-19...
The Biogerontology Research Foundation, a registered UK charity supporting and promoting aging and longevity research worldwide since 2008, today announced the publication of a paper titled...
View ArticleUC study tests efficacy of immune regulating drug in treating patients with...
Researchers at the University of Cincinnati are testing a commonly used drug, called sirolimus, to determine its safety and efficacy in treating hospitalized patients with COVID-19 pneumonia in the trial.
View ArticleStudy explores therapeutic potential of exploiting autophagy cascade against...
Researchers recently reviewed current knowledge on links between autophagy and coronaviruses and how this knowledge can be used to repurpose autophagy modulators as potential treatment options for...
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